Where there is automatic detection, does the system always require manual call points?

Thanks.  

Assuming this is not domestic premises, flats, etc:

Yes, unless it's a property protection system not intended for the preservation of life.

A fire alarm system starts with manual fire warning and call points and sounders are always the starting point to meet legislation and has been the case for over 50 years.

In most buildings you can stop there and you only need to add detection if there is a specific risk requiring it (e.g. inner rooms, sleeping risk, etc)